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human neuronal stem cells  (Cell Applications Inc)


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    Cell Applications Inc human neuronal stem cells
    Human Neuronal Stem Cells, supplied by Cell Applications Inc, used in various techniques. Bioz Stars score: 93/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human neuronal stem cells/product/Cell Applications Inc
    Average 93 stars, based on 3 article reviews
    human neuronal stem cells - by Bioz Stars, 2026-05
    93/100 stars

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    Processing of amyloid precursor protein (APP) and glypican‐1 (GPC1) in late endosomes (top) and phosphorylation of cytosolic tau (bottom). β‐NTF and β‐CTF, N‐terminal and C‐terminal APP fragments, respectively; Aβ, amyloid beta peptides; HS‐anMan, heparan sulfate with reducing terminal anhydromannose (blue pentagon); SNO, nitrosothiol; SH, thiol; N =N, molecular nitrogen generated from SNO in the redox reaction; Asc, ascorbate; GPI, glycosyl‐phophatidyl‐inositol; Red squares in tau, microtubule‐binding region; P , phosphate groups. GPC1 is the major, if not exclusive, source of HS‐anMan in human neural progenitor cells and neural stem cells (Cheng et al. , ).

    Journal: Journal of Neurochemistry

    Article Title: Modulation of pTau181 by Glypican‐1‐Derived Heparan Sulfate in Human Neural Progenitor Cells and ApoE4 ‐Expressing Induced Neurons

    doi: 10.1111/jnc.70162

    Figure Lengend Snippet: Processing of amyloid precursor protein (APP) and glypican‐1 (GPC1) in late endosomes (top) and phosphorylation of cytosolic tau (bottom). β‐NTF and β‐CTF, N‐terminal and C‐terminal APP fragments, respectively; Aβ, amyloid beta peptides; HS‐anMan, heparan sulfate with reducing terminal anhydromannose (blue pentagon); SNO, nitrosothiol; SH, thiol; N =N, molecular nitrogen generated from SNO in the redox reaction; Asc, ascorbate; GPI, glycosyl‐phophatidyl‐inositol; Red squares in tau, microtubule‐binding region; P , phosphate groups. GPC1 is the major, if not exclusive, source of HS‐anMan in human neural progenitor cells and neural stem cells (Cheng et al. , ).

    Article Snippet: For dissociation and re‐plating, Accutase (Fisher Scientific Cat. # 11599686) was used as described in detail previously (Cheng et al. ). iPSC‐derived human neuronal progenitor cells (NPC, ATCC, Cat. # ACS‐5003) were plated in CellMatrix gel‐coated plates (Growth kit ACS‐3003 for NPC expansion).

    Techniques: Phospho-proteomics, Generated, Binding Assay